Biophysics (BIP)
Section Information
Biophysics applies the principles and methods of physics to understand how biological molecules, cells, and systems function. It connects structure, dynamics, and energetics to explain how life processes emerge from physical interactions at molecular and cellular scales.
Modern biophysics uses experimental, theoretical, and computational tools to study biomolecular folding, interactions, mechanical properties, membrane behavior, signaling, and the physics of living systems. Techniques such as spectroscopy, single-molecule methods, imaging, and simulations help reveal mechanisms that are not accessible through traditional biological approaches alone.
This section will publish research articles, short communications, and reviews on molecular and cellular biophysics, structural and computational biophysics, bioenergetics, biomechanics, soft matter systems, quantitative imaging, and integrative studies that deepen our physical understanding of life.
Scope
- Molecular Biophysics
- Structure, dynamics, and energetics of biomolecules
- Protein folding, stability, and conformational transitions
- Ligand binding, allostery, and molecular recognition
- Interactions within macromolecular complexes
- Membrane Biophysics
- Lipid bilayers, membrane proteins, and transport processes
- Channels, pumps, and ion transport mechanisms
- Membrane curvature, domains, and organization
- Biophysical approaches to signaling across membranes
- Cellular and Systems Biophysics
- Mechanical properties of cells and cytoskeleton
- Force generation, motility, and mechanotransduction
- Biophysical control of cell shape, division, and organization
- Quantitative models of cellular processes and networks
- Bioenergetics and Metabolic Biophysics
- Energy transduction, redox processes, and electron transport
- Thermodynamics of biochemical reactions and pathways
- Coupling of metabolism with cellular and molecular processes
- Biophysical methods for studying metabolic dynamics
- Single-Molecule and High-Resolution Techniques
- Single-molecule fluorescence, force spectroscopy, and tracking
- Super-resolution and advanced optical imaging
- Label-free and nanoscale biophysical measurements
- Integration of single-molecule data with structural and functional models
- Computational and Theoretical Biophysics
- Molecular dynamics simulations and enhanced sampling
- Coarse-grained, multiscale, and continuum modeling
- Theoretical frameworks for biomolecular folding and interactions
- Data-driven and machine learning approaches in biophysics
- Biophysics of Soft Matter and Complex Systems
- Self-assembly, phase behavior, and emergent properties
- Viscoelasticity, rheology, and colloidal interactions
- Active matter and nonequilibrium biological systems
- Biophysical principles underlying collective behavior
- Applied and Interdisciplinary Biophysics
- Biophysical methods in biotechnology and medicine
- Diagnostics, biomaterials, and therapeutic design
- Biophysical insights for synthetic and engineered systems
- Cross-disciplinary studies linking physics, chemistry, and biology
Editorial Board
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Topical Advisory Panel
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Papers Published
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