Microscopy (MIS)
Section Information
Microscopy focuses on the techniques, instruments, and analytical methods used to visualize and study structures at micro- to nanoscale resolution. It encompasses optical, electron, scanning probe, and hybrid imaging methods that support research across biology, materials science, medicine, chemistry, and nanotechnology.
Modern research in this field includes high-resolution and super-resolution imaging, cryogenic microscopy, correlative imaging workflows, 3D and volumetric microscopy, quantitative image analysis, advanced probes and labeling strategies, and in situ and in vivo imaging. Ongoing advances in instrumentation, detectors, computational processing, and automation continue to expand the capabilities of microscopy.
This section publishes experimental studies, methodological developments, imaging innovations, computational tools, reviews, and application-based research that enhance imaging performance, improve structural and functional analysis, and support interdisciplinary scientific discovery.
Scope
- Optical and Super-Resolution Microscopy
- Widefield, confocal, multiphoton, and light-sheet microscopy
- Super-resolution methods such as STED, SIM, PALM, and STORM
- Fluorescent probes, live-cell imaging, and photophysics
- Optical sectioning, 3D imaging, and advanced illumination techniques
- Electron Microscopy
- Transmission (TEM), scanning (SEM), and cryo-electron microscopy (cryo-EM)
- Tomography, diffraction methods, and high-resolution structural studies
- Sample preparation, staining, and cryogenic workflows
- Materials characterization and ultrastructural analysis
- Scanning Probe Microscopy
- Atomic force microscopy (AFM), STM, and related techniques
- Nanoscale mechanical, electrical, and chemical mapping
- Probe design, tip–sample interactions, and quantitative imaging
- Applications in biology, nanoscience, and materials research
- Correlative and Multimodal Imaging
- Correlative light and electron microscopy (CLEM)
- Integration of optical, electron, and spectroscopic techniques
- Workflow design for multi-scale structural and functional studies
- Combined imaging for biological, medical, and materials applications
- Labeling, Contrast Mechanisms, and Probes
- Fluorescent dyes, proteins, and nanoparticles
- Immunolabeling, chemical tagging, and reporter systems
- Phase, polarization, and scattering-based contrast methods
- Development of novel probes for targeted imaging
- Image Processing, Analysis, and Computational Microscopy
- Image reconstruction, denoising, segmentation, and quantification
- Machine learning, AI-driven analysis, and automated workflows
- Inverse imaging problems and computational optics
- Big data management, visualization, and reproducible pipelines
- In Situ, In Vivo, and Functional Microscopy
- Real-time imaging of dynamic biological and chemical processes
- Environmental and variable-condition microscopy for materials
- Functional imaging of molecular interactions and cellular behavior
- Microscopy for medical diagnostics and physiological monitoring
- Instrumentation, System Design, and Performance Evaluation
- Optical systems, detectors, lasers, and hardware integration
- Microscope calibration, resolution assessment, and quality metrics
- Custom-built microscopy platforms and open-source instrumentation
- Engineering advances enabling higher speed, resolution, and sensitivity
Editorial Board
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Topical Advisory Panel
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Papers Published
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